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    近五年,课程组教师共发表96篇学术论文,其中SCI文章33篇,北图核心48(*通讯作者,

 **SCI论文,IF=影响因子),人均证实发表论文7篇。课程组教师发表教学改革论文5篇。

 

                 学术论文

 

序号

论文题目

作者

杂志名、年、页

1

Short-term assessment of BCR repertoires of 

SLE patients after high dose glucocorticoid

 therapy with high-throughput sequencing.

Shi B, Yu J, Ma L, Ma Q, 

Liu C, Sun S, 

Ma R, XinSheng Y*.

Springerplus. 2016, 5:75.** 

2

TRBV gene expression in PBMCs and TILs 

in patients with infiltrating ductal breast carcinomas 

analyzed by a DNA melting curve (FQ-PCR) technique using TCR beta chain CDR3

 spectratyping.Journal of Zunyi Medical University. 

He Xiaoyan,Sun Suhong, 

Yang Weiming, 

Tang Wentai, Ma Rui, 

Zhang Tian, XinSheng Y*.

Journal of Zunyi Medical 

University.  2016 Jan, 39:35-43.**

3

Analyzing the CDR3 Repertoire with respect to TCR Beta Chain V-D-J and V-J Rearra-

ngements in Peripheral T Cells using HTS.

Long Ma, Liwen Yang, 

Bin Shi, Xiaoyan He, 

Aihua Peng, Yuehong Li, 

Teng Zhang, Suhong Sun, 

Rui Ma, Xinsheng Yao*

Scientific Reports. 2016(06 ).**  IF=5.3

4

Antisense oligonucleotides against microRNA-21 reduced the proliferation and migration of human colon carcinoma cells .

Tao YJ, Li YJ, Zheng W, Zhao JJ, Guo MM, Zhou Y, Qin NL, Zheng J, Xu L*.

Cancer cell international. 2015, 15:77**

5

MicroRNA-7: a promising new target in cancer therapy.

Zhao J, Tao Y, Zhou Y, Qin N, Chen C, Tian D, Xu L*

Cancer cell international 2015, 15:103.

6

MiR-21 controls in situ expansion of CCR6+ regulatory T cells through PTEN/AKT pathway in breast cancer.

Hu YWang CLi YZhao JChen C

Zhou YTao YGuo MQin NRen TWen ZXu L* .

Immunol Cell Biol. 2015 .

Mar 4. **IF=4.20

 

7

Gab2 facilitates epithelial-to-mesenchymal 

transition via the MEK/ERK/MMP signaling

 in colorectal cancer

Ding CLuo J(共第一作者)Li L,  Li S, Yang L, Pan H, Liu Q, 

Qin H, Chen C, Feng J.

J Exp Clin Cancer Res,

 2016, 35(1):5. **

 

8

Composition and variation analysis  of TCR β-chain CDR3 repertoire in the thymus and spleen of MRL/lpr mouse at different ages. Immunogenetics. 

Li ZLong MChun MeiLBin SJiang YRui MQingqing MXinSheng Y*.

Immunogenetics. 2015 Jan;67(1):25-37. ** IF=2.49

 

9

Gab2 is a novel prognostic factor for colorectal cancer patients.

Ding C, Luo J*, Yu W, Gao S, Yang L, Chen C, Feng J

Int J Clin Exp Pathol. 2015, 8(3):2779-2786. **IF=1.89

10

Structure and function of Gab2 and its role in cancer (Review).

Ding CB, Yu WN, Feng JH, Luo JM*.

2015 Jun 17. **IF=1.55

11

Genome editing-based HIV therapies.

Gu WG.

Trends Biotechnol. 2015 Mar;33(3):172-9. **IF=10.04

12

Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development.

Gu WG.Liu BN, Yuan JF

Journal of drug targeting 2015, 23(2):134-139. **

 

13

Newly approved integrase inhibitors for clinical treatment of AIDS.

Gu WG.

Biomed  Pharmacother. 

2014  Oct;68(8):917-21. **IF=2.11

14

Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging.

Gu WG, Zhang XIp DTYang LMZheng YTWan DC.

FEBS Lett. 2014 Sep 17;588(18):3461-8. **IF=3.34

15

Virtual-screening targeting Human Immunodeficiency Virus type 1 integrase-lens epithelium-derived growth factor/p75 interaction for drug development.

GuWGLiu BNYuan JF.

J Drug Target. 2015 Feb; 23(2):134-9. **IF=2.72

 

16

1,4-bis(5-(naphthalen-1-yl) thiophen-2-yl) naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor.

Gu WG, IpDT, Liu SJChan JH, Wang Y, Zhang X, Zheng YT, Wan DC.

Chemico-Biological Interactions, 2014,

213:21-27. **IF=2.97

 

17

Targeting CCR5 for anti-HIV research.

Gu WG, Chen XQ*.

Eur J Clin Microbiol Infect Dis. 2014 Jun 11. ** IF=3.02

 

18

Anti-HIV Drug Development Through Computational Methods.

Gu WG, Zhang X, Yuan JF.

AAPS J.2014,16(4):

674-680. **IF=4.39

 

19

MicroRNAs expression profile in CCR6+ regulatory T cells.

Zhao JLi YHu YChen CZhou YTao YGuo MQin NXu L*.

PeerJ. 2014 Sep 18; 2:e575. 

20

Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST.

ShiB,MaL,HeX,WangX,

WangP,ZhouL,YaoX*.

Theor Biol Med Model. 2014,11(1):30. **IF=1.46

 

21

Requirement of TPO/c-mpl for IL-17A-induced granulopoiesis and megakaryopoiesis. Journal of Leukocyte Biology.

Weihong Tan, Bainan Liu(Co-first author), Adel Barsoum, Weitao Huang, JK Kolls, Paul Schwarzenberger.

Epub ahead of print. August 2013. ** IF=4.57

22

Immunotherapy treatments of warm autoimmune

 hemolytic anemia. 

Liu BN, Gu WG.

Clin Dev Immunol. 2013;2013:561852. ** IF=3.06

23

TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells.

Li Y, Wang C, Zhou Y, Liao Z, Zhu S, Hu Y, Chen C, Luo J, Wen Z, Xu L*.

Canc Cell Int, 2013. 13(1):90. ** IF=2.09

24

MicroRNA-126 regulates the induction and function of CD4+ Foxp3+ regulatory T cells through PI3K/AKT pathway.

Qin A, Wen Z, Zhou Y, Li Y, Li Y, Luo J, Ren T, Xu L*.

J Cell Mol Med. 2013; 17(2):252-64.** IF=4.75

 

25

Antisense oligonucleotides treatment enhanced the recovery of acute lung injury through IL-10 secreting M2 like macrophages-induced expansion of CD4+ regulatory T cells.

Guo ZL, Wen ZK, Qin AD, Zhou Y, Ren T, Xu L*.

J Immunol, 2013, 190(8): 4337-48. ** IF=5.52

26

IL-17A/IL-17RA interaction promoted metastasis of osteosarcoma cells.

Wang M, Wang L, Ren T, Xu L*, Wen Z.

Cancer Biol Ther. 2013;14(2):155-63 ** IF=3.28

27

MicroRNA-7 regulated TLR9 signaling enhanced growth and metastatic potential of human lung cancer cells by altering PIK3R3/Akt pathway.

Xu L, Wen Z, Zhou Y, Liu Z, Li Q, Fei G, Luo J, Ren T.

Mol Bio Cell. 2013. 24(1):42-55. ** IF=4.6

 

28

Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA.

Wen Z, Xu L, Xu W, Yin Z, Gao X, Xiong S.

PLoS One. 2013;8(3): e58161. ** IF=3.73

 

29

TRAV gene expression in PBMCs and TILs in patients with breast cancer analyzed by DNA melting curve (FQ-PCR) technique for TCR alpha chain CDR3 spectratyping.

He XY, Yang WM, Tang WT, Ma R, Sun YP, Wang P, Yao XS*.

Neoplasma, 2012;59(6): 693-699. ** IF=1.57

 

30

Critical role of Th17 cells in development of autoimmune hemolytic anemia.

Xu L, Zhang T, Liu Z, Li Q, Xu Z, Ren T.

Exp Hematol. 2012, 40(12):994-1004.e4. ** IF=2.91

 

31

CpG oligonucleotides induce the differentiation of CD4(+)Th17 cells by triggering plasmacytoid dendritic cells in adoptively cell transfer immunotherapy.

Xu L, Wang C, Zhou Y, Ren T, Wen Z.

Immunol Lett.2012; 142(1-2):55-63.** IF=2.34

 

32

Primary Exploration of the Third Complementarity Determining Region 3 Spectratyping and Molecular Features of T Cell Receptor Alpha Chain in the Peripheral Blood and Tissue of Patients with Colorectal Carcinoma.

Zhou JW, Ma R, Tang WT, Luo R , Luo JM, Yao XS *.

Acta Medica Mediterranea, 2011, 27: 23-30.

33

In situ prior proliferation of CD4+ CCR6+ regulatoryT cells facilitated by TGF-secreting DCs is crucial for their enrichment and suppression in tumor immunity.

Xu L, Xu W, Wen Z, Xiong S.

PLoS One. 2011;6 (5):e20282.

 

                    教学改革论文

序号

论文题目

作者

杂志名、年、页

1

浅谈加强信息素质教育对医学生科研能力培养的作用.

覃明, 罗军敏, 姚新生, 徐林, 陈富超,汤贤英

黔南民族医专学报,2011,243:229-230

2

构建“以学生为主体”的本科医学免疫学实验教学模式

秦娜琳,罗军敏,姚新生,孙万邦,郑静,田丹,覃明,陈富超

中国免疫学杂志,2012285):465-466

3

基于RGSE 模式的本科免疫学实践教学改革的初探

徐林,罗军敏,秦娜琳,田丹,覃明,陈富超,郑静

中国免疫学杂志,2013297):755-758

4

推行免疫学实验教学改革提高学生科研兴趣

刘白南,罗军敏,杨鸣,田丹,郑静

教育教学论坛,201342261-262

5

基于卓越医师计划的医学免疫学实验教学改革

张忆雄,徐林,罗军敏,秦娜琳,马龙

教育教学论坛,201442118-119

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